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Article

Differential expression of immunoregulatory genes in male and female Norway rats following infection with Seoul virus

13 Jul 2004

Abstract excerpt

Males of many species are more susceptible than females to infections caused by parasites, bacteria, fungi, and viruses. Following inoculation with Seoul virus, male rats have more virus present in target organs and shed virus longer than females. The goal of this study was to test the hypothesis that variation in the expression of genes associated with immune function mediates sex differences in hantavirus...

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PMID: 15258986
DOI: 10.1002/jmv.20163

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