Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Drosophila selenophosphate synthetase (selD) gene is required for development and cell proliferation.

BioFactors (Oxford, England) - 1 Jan 2001

Serras F, Morey M, Alsina B, Baguñà J, Corominas M

Abstract excerpt

To study the function of selenoproteins in development and growth we have used a lethal mutation (selD(ptuf)) of the Drosophila homologous selenophosphate synthetase (selD) gene. This enzyme is involved in the selenoprotein biosynthesis. The selD(ptuf) loss-of-function mutation causes aberrant cell proliferation and differentiation patterns in the brain and imaginal discs, as deduced from genetic mosaics,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila Proteins
Share to Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genes, Lethal

Share to Genomic Imprinting

Share to Mosaicism

Share to Phosphotransferases

Share to Protein Biosynthesis

Share to Selenoproteins

Source

Identifiers

PMID: 11568451
DOI: 10.1002/biof.5520140119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Drosophila selenophosphate synthetase (selD) gene is required for development and cell proliferation.PMID 11568451Read ↗

Modulation of the Ras/MAPK signalling pathway by the redox function of selenoproteins in Drosophila melanogaster.Semantic proximity Read ↗

Sply regulation of sphingolipid signaling molecules is essential for Drosophila development.Semantic proximity Read ↗

DIAP1 suppresses ROS-induced apoptosis caused by impairment of the selD/sps1 homolog in Drosophila.Semantic proximity Read ↗

The Drosophila dual-specificity ERK phosphatase DMKP3 cooperates with the ERK tyrosine phosphatase PTP-ER.Semantic proximity Read ↗

De novo synthesis of sphingolipids is required for cell survival by down-regulating c-Jun N-terminal kinase in Drosophila imaginal discs.Semantic proximity Read ↗

Pink-eyed dilution protein modulates arsenic sensitivity and intracellular glutathione metabolism.Semantic proximity Read ↗

Identification and characteristics of the structural gene for the Drosophila eye colour mutant sepia, encoding PDA synthase, a member of the omega class glutathione S-transferases.Semantic proximity Read ↗

Characterization of the Drosophila sphingosine kinases and requirement for Sk2 in normal reproductive function.Semantic proximity Read ↗

Expanded: a gene involved in the control of cell proliferation in imaginal discs.Semantic proximity Read ↗

Fetal mouse selenophosphate synthetase 2 (SPS2): biological activities of mutant forms in Escherichia coli.Semantic proximity Read ↗

Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila.Semantic proximity Read ↗

Deletion of selenoprotein P alters distribution of selenium in the mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.