Article
Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development.
Development (Cambridge, England) - 1 Sept 2001
Inbal A, Halachmi N, Dibner C, Frank D, Salzberg A
Abstract excerpt
Homothorax (HTH) is a homeobox-containing protein, which plays multiple roles in the development of the embryo and the adult fly. HTH binds to the homeotic cofactor Extradenticle (EXD) and translocates it to the nucleus. Its function within the nucleus is less clear. It was shown, mainly by in vitro studies, that HTH can bind DNA as a part of ternary HTH/EXD/HOX complexes, but little is known about the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
