Article
Genetic evidence for the transcriptional-activating function of Homothorax during adult fly development.
Development (Cambridge, England) - 1 Sept 2001
Inbal A, Halachmi N, Dibner C, Frank D, Salzberg A
Abstract excerpt
Homothorax (HTH) is a homeobox-containing protein, which plays multiple roles in the development of the embryo and the adult fly. HTH binds to the homeotic cofactor Extradenticle (EXD) and translocates it to the nucleus. Its function within the nucleus is less clear. It was shown, mainly by in vi...
Topics
- Amino Acid Sequence
- Animals
- Animals, Genetically Modified
- Cell Nucleus
- Conserved Sequence
- Drosophila Proteins
- Drosophila melanogaster
- Evolution, Molecular
- Extremities
- Herpes Simplex Virus Protein Vmw65
- Homeodomain Proteins
- Phenotype
- Protein Transport
- Recombinant Fusion Proteins
- Repressor Proteins
- Transcription Factors
- Transcriptional Activation
- Xenopus Proteins
