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Article

The TALE transcription factor homothorax functions to assemble heterochromatin during Drosophila embryogenesis.

PloS one - 1 Jan 2015

Zaballos Miguel Angel, Cantero Walter, Azpiazu Natalia

Abstract excerpt

We have previously identified Homothorax (Hth) as an important factor for the correct assembly of the pericentromeric heterochromatin during the first fast syncytial divisions of the Drosophila embryo. Here we have extended our studies to later stages of embryonic development. We were able to show that hth mutants exhibit a drastic overall reduction in the tri-methylation of H3 in Lys9, with no reduction of the...

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Identifiers

PMID: 25794008
DOI: 10.1371/journal.pone.0120662
PMCID: PMC4368669

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Source receipt: pubmed, retrieved 7 Sept 2026.

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