Article
extradenticle determines segmental identities throughout Drosophila development.
Development (Cambridge, England) - 1 Nov 1995
Rauskolb C, Smith K M, Peifer M, Wieschaus E
Abstract excerpt
extradenticle (exd) and the homeotic selector proteins together establish segmental identities by coordinately regulating the expression of downstream target genes. The inappropriate expression of these targets in exd mutant embryos results in homeotic transformations and aberrant morphogenesis. Here we examine the role of exd in adult development by using genetic mosaics and a hypomorphic exd allele caused by a...
Topics
- Alleles
- Animals
- Cloning, Molecular
- DNA-Binding Proteins
- Drosophila
- Drosophila Proteins
- Extremities
- Gene Expression
- Genes, Homeobox
- Genes, Insect
- Homeodomain Proteins