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Reduced susceptibility to tetracyclines is associated in vitro with the presence of 16S rRNA mutations in Mycoplasma hominis and Mycoplasma pneumoniae

13 Mar 2008

Abstract excerpt

Sir, Mycoplasma pneumoniae and Mycoplasma hominis are aetiological agents of respiratory and genitourinary tract infections, respectively, for which tetracyclines present potential for empirical treatment.1 As mycoplasmas possess a small number of rrn operons, one for M. pneumoniae and two for M. hominis, the target-related mechanism of resistance to tetracyclines caused by 16S rRNA mutations could be expected as...

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PMID: 18356155
DOI: 10.1093/jac/dkn118

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