Article
Molecular characterization of macrolide resistance of a Mycoplasma pneumoniae strain that developed during therapy of a patient with pneumonia.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Dec 2014
Dumke Roger, Stolz Simone, Jacobs Enno, Juretzek Thomas
Abstract excerpt
The development of macrolide resistance that occurred during 3 days of therapy with azithromycin to treat Mycoplasma pneumoniae pneumonia in a paediatric patient is reported. After extended molecular characterization of strains, the parallel occurrence of clones showing the non-mutated wild-type 23S rRNA sequence as well as mutations A2063G and A2064G, which are both responsible for phenotypic resistance, was...
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