Article
HLA-DQ alleles in patients with celiac disease in Turkey.
Tissue antigens - 1 Jun 2001
Tüysüz B, Dursun A, Kutlu T, Sökücü S, Cine N, Süoğlu O, Erkan T, Erginel-Unaltuna N, Tümay G
Abstract excerpt
The prevalence of the HLA-DQA1 and DQB1 alleles in 55 Turkish children with celiac disease and 50 control subjects was investigated by using an allele-specific DNA-based polymerase chain reaction-sequence-specific primer (PCR-SSP) method. The frequency of the DQA1*0501 and DQB1*02 alleles was higher in celiac patients than in controls. The DQA1B1 (*0501; *02) haplotype was present in 46 (83.6%) patients and only...
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