Article
Utility of the Arg/Gln polymorphism of the factor VII (FVII) gene, serum lipid levels and body mass index in the prediction of the FVII:C and FVII:Ag in North Karelia; a cross-sectional and prospective study.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Sept 2001
Stengård J H, Salomaa V, Rasi V, Vahtera E, Ehnholm C, Krusius T, Perola M, Vartiainen E
Abstract excerpt
The arginine/glutamine (Arg/Gln) polymorphism of the factor VII (FVII) gene is associated with variation in coagulation activity (FVII:C) and antigen concentration (FVII:Ag) of the FVII protein. We estimated frequency distributions of the Arg and Gln alleles and respective genotypes in North Karelia, and evaluated the utility of this polymorphism, serum lipids, and body mass index (BMI) in the prediction of the...
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