Genetic polymorphism (Arg353-->Gln) in coagulation factor VII gene and factor VII levels (coagulant activity, antigen and binding ability to tissue factor) in 101 healthy Japanese.

Abstract excerpt

We studied the frequency of the Msp I genotype (Gln353) for factor VII in 101 young healthy Japanese individuals, and the levels of factor VII-related procoagulant activity (FVII:c), antigen (FVII:ag) and binding ability to tissue factor (FVII-TF binding). The frequency of the allele coding for t...

Topics

• Adult
• Antigens
• Asian People
• DNA
• Factor VII
• Female
• Genotype
• Humans
• Japan
• Male
• Middle Aged
• Polymerase Chain Reaction
• Polymorphism, Genetic