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Article

In primary Sjögren's syndrome, HLA class II is associated exclusively with autoantibody production and spreading of the autoimmune response.

Arthritis and rheumatism - 1 Aug 2003

Gottenberg Jacques-Eric, Busson Marc, Loiseau Pascale, Cohen-Solal Julien, Lepage Virginia, Charron Dominique, Sibilia Jean, Mariette Xavier

Abstract excerpt

OBJECTIVE: To reevaluate, in a large series of patients with Sjögren's syndrome (SS) recruited from 2 French centers, the question of whether HLA is associated with SS itself or with a pattern of secretion of autoantibodies. METHODS: One hundred forty-nine white patients fulfilling the American-European Consensus Group criteria for SS were divided into 3 subgroups, according to their anti-Ro/SSA and anti-La/SSB...

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Source

Identifiers

PMID: 12905478
DOI: 10.1002/art.11103

Genes

SSB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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