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Article

Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras.

The Journal of biological chemistry - 16 Nov 2001

Kampfer S, Windegger M, Hochholdinger F, Schwaiger W, Pestell R G, Baier G, Grunicke H H, Uberall F

Abstract excerpt

Transcriptional activation of the cyclin D1 by oncogenic Ras appears to be mediated by several pathways leading to the activation of multiple transcription factors which interact with distinct elements of the cyclin D1 promoter. The present investigations revealed that cyclin D1 induction by transforming Ha-Ras is MEK- and Rac-dependent and requires the PKC isotypes epsilon, lambda, and zeta, but not cPKC-alpha....

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Identifiers

PMID: 11551901
DOI: 10.1074/jbc.M102047200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protein kinase C isoforms involved in the transcriptional activation of cyclin D1 by transforming Ha-Ras.PMID 11551901Read ↗

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