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Article

Integration of Rac-dependent regulation of cyclin D1 transcription through a nuclear factor-kappaB-dependent pathway.

The Journal of biological chemistry - 3 Sept 1999

Joyce D, Bouzahzah B, Fu M, Albanese C, D'Amico M, Steer J, Klein J U, Lee R J, Segall J E, Westwick J K, Der C J, Pestell R G

Abstract excerpt

The small GTP-binding protein Rac1, a member of the Ras superfamily, plays a fundamental role in cytoskeleton reorganization, cellular transformation, the induction of DNA synthesis, and superoxide production. Cyclin D1 abundance is rate-limiting in normal G(1) phase progression, and the abundanc...

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Source

Identifiers

PMID: 10464245
DOI: 10.1074/jbc.274.36.25245

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10464245-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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