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Article

Absence of cardiac lipid accumulation in transgenic mice with heart-specific HSL overexpression.

American journal of physiology. Endocrinology and metabolism - 1 Oct 2001

Suzuki J, Shen W J, Nelson B D, Patel S, Veerkamp J H, Selwood S P, Murphy G M, Reaven E, Kraemer F B

Abstract excerpt

Hormone-sensitive lipase (HSL) hydrolyzes triglyceride (TG) in adipose tissue. HSL is also expressed in heart. To explore the actions of cardiac HSL, heart-specific, tetracycline (Tc)-controlled HSL-overexpressing mice were generated. Tc-responsive element-HSL transgenic (Tg) mice were generated and crossed with myosin heavy chain (MHC)alpha-tTA Tg mice, which express the Tc-responsive transactivator (tTA) in the...

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Identifiers

PMID: 11551864
DOI: 10.1152/ajpendo.2001.281.4.E857

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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