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Article

Transgenic mice expressing lipoprotein lipase in adipose tissue. Absence of the proximal 3'-untranslated region causes translational upregulation.

The Journal of biological chemistry - 29 Aug 2003

Hensley Lori L, Ranganathan Gouri, Wagner Elke M, Wells Brian D, Daniel Joseph C, Vu Diane, Semenkovich Clay F, Zechner Rudolf, Kern Philip A

Abstract excerpt

Lipoprotein lipase (LPL) is a key enzyme in lipoprotein and adipocyte metabolism. Defects in LPL can lead to hypertriglyceridemia and the subsequent development of atherosclerosis. The mechanisms of regulation of this enzyme are complex and may occur at multiple levels of gene expression. Because...

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Source

Identifiers

PMID: 12796491
DOI: 10.1074/jbc.M304200200

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12796491-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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