Combinatorial protein design by in vitro recombination.

doi:10.1016/s1367-5931(98)80006-9

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Article

Combinatorial protein design by in vitro recombination.

Current opinion in chemical biology - 1 Jun 1998

Giver L, Arnold F H

Abstract excerpt

DNA recombination is a powerful engine for the creation of new phenotypes. Recently, methods for in vitro DNA recombination (DNA shuffling) have been developed and applied to the evolution of novel molecules in the laboratory. An exciting new development is the shuffling of homologous genes to cr...

Topics

DNA
DNA, Recombinant
Directed Molecular Evolution
Drug Design
Genetic Variation
Protein Biosynthesis
Proteins
Recombinant Fusion Proteins
Recombinant Proteins
Recombination, Genetic

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