Article
Combinatorial protein design by in vitro recombination.
Current opinion in chemical biology - 1 Jun 1998
Giver L, Arnold F H
Abstract excerpt
DNA recombination is a powerful engine for the creation of new phenotypes. Recently, methods for in vitro DNA recombination (DNA shuffling) have been developed and applied to the evolution of novel molecules in the laboratory. An exciting new development is the shuffling of homologous genes to create diversity for directed evolution.
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