Article
Neurogenin 1 null mutant ears develop fewer, morphologically normal hair cells in smaller sensory epithelia devoid of innervation.
Journal of the Association for Research in Otolaryngology : JARO - 1 Sept 2000
Ma Q, Anderson D J, Fritzsch B
Abstract excerpt
The proneuronal gene neurogenin 1 (ngn1) is essential for development of the inner-ear sensory neurons that are completely absent in ngn1 null mutants. Neither afferent, efferent, nor autonomic nerve fibers were detected in the ears of ngn1 null mutants. We suggest that efferent and autonomic fib...
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