Article
African diversity from the HLA point of view: influence of genetic drift, geography, linguistics, and natural selection.
Human immunology - 1 Sept 2001
Sanchez-Mazas A
Abstract excerpt
This study investigates the influence of different evolutionary factors on the patterns of human leukocyte antigen (HLA) genetic diversity within sub-Saharan Africa, and between Africa, Europe, and East Asia. This is done by comparing the significance of several statistics computed on equivalent population data sets tested for two HLA class II loci, DRB1 and DPB1, which strongly differ from each other by the...
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