Article
HLA class-I diversity in Cameroon: evidence for a north-south structure of genetic variation and relationships with African populations.
Annals of human genetics - 1 Nov 2011
Spínola Hélder, Couto Ana Rita, Peixoto Maria José, Anagnostou Paolo, Destro-Bisol Giovanni, Spedini Gabriella, Lopéz-Larrea Carlos, Bruges-Armas Jácome
Abstract excerpt
HLA class I diversity (loci A, B and C) was analysed in four populations, two from North Cameroon (Podokwo and Uldeme) and two from South Cameroon (Ewondo and Bamileke). Northern and southern Cameroon populations show a substantial genetic diversity in terms of haplotype sharing and genetic distances, even despite the low percentage of variance due to differences among populations evidenced by analysis of...
Topics
- Africa South of the Sahara
- Africa, Southern
- Black People
- Cameroon
- Gene Frequency
- Genes, MHC Class I
- Genetic Variation
- Haplotypes
- Humans