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Article

Catalytic roles of yeast GSK3beta/shaggy homolog Rim11p in meiotic activation.

Genetics - 1 Nov 1999

Malathi K, Xiao Y, Mitchell A P

Abstract excerpt

In Saccharomyces cerevisiae, many meiotic genes are activated by a heteromeric transcription factor composed of Ime1p and Ume6p. Ime1p-Ume6p complex formation depends upon the protein kinase Rim11p, which interacts with and phosphorylates both Ime1p and Ume6p in vitro. Rim11p may promote complex formation through its phosphorylation of Ime1p and Ume6p or simply through its interaction with both proteins. Here, we...

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Identifiers

PMID: 10545448
DOI: 10.1093/genetics/153.3.1145
PMCID: PMC1460824

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