Article
The operator-early promoter regions of Shiga-toxin bearing phage H-19B.
Molecular microbiology - 1 Aug 2001
Shi T, Friedman D I
Abstract excerpt
Genes (stx) encoding Shiga toxins (Stx), major virulence factors in some pathogenic strains of Escherichia coli (STEC), are located in prophages of the lambda family. Agents that induce prophages lead to high levels of Stx, suggesting a role for the prophage in stx expression. Activation of the phage regulatory cascade has been shown to contribute to Stx production and release. Therefore, repressor-operator...
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