Article
The operator and early promoter region of the Shiga toxin type 2-encoding bacteriophage 933W and control of toxin expression.
Journal of bacteriology - 1 Nov 2004
Tyler Jessica S, Mills Melissa J, Friedman David I
Abstract excerpt
The genes encoding Shiga toxin (Stx), the major virulence factor of Shiga toxin-producing Escherichia coli, are carried in the genomes of bacteriophages that belong to the lambdoid family of phages. Previous studies demonstrated that induction of prophages encoding stx significantly enhances the production and/or release of Stx from the bacterium. Therefore, factors that regulate the switch between lysogeny and...
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