Article
N-mediated transcription antitermination in lambdoid phage H-19B is characterized by alternative NUT RNA structures and a reduced requirement for host factors.
Molecular microbiology - 1 Dec 2000
Neely M N, Friedman D I
Abstract excerpt
Gene expression in lambdoid phages in part is controlled by transcription antitermination. For most lambdoid phages, maximal expression of delayed early genes requires an RNA polymerase modified by the phage N and host Nus proteins at RNA NUT sites. The NUT sites (NUTL and NUTR) are made up of three elements: BOXA, BOXB and an intervening spacer sequence. We report on N antitermination in H-19B, a lambdoid phage...
Topics
- Bacteriophage lambda
- Base Sequence
- Escherichia coli
- Molecular Sequence Data
- Mutation
- Nucleic Acid Conformation
- Plasmids
- RNA, Bacterial
- Terminator Regions, Genetic
- Transcription, Genetic