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Bacteriophages of Shiga Toxin-Producing Escherichia coli and Their Contribution to Pathogenicity

29 Mar 2021

Abstract excerpt

Shiga toxins (Stx) of Shiga toxin-producing Escherichia coli (STEC) are generally encoded in the genome of lambdoid bacteriophages, which spend the most time of their life cycle integrated as prophages in specific sites of the bacterial chromosome. Upon spontaneous induction or induction by chemical or physical stimuli, the stx genes are co-transcribed together with the late phase genes of the prophages. After...

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PMID: 33805526
DOI: 10.3390/pathogens10040404

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