Article
Role for a Phage Promoter in Shiga Toxin 2 Expression from a Pathogenic <i>Escherichia coli</i> Strain
15 Mar 2001
Abstract excerpt
Shiga toxins (Stxs), encoded by the stxA and stxB genes, are important contributors to the virulence of Escherichia coli O157:H7 and other Stx-producing E. coli (STEC) strains. The stxA and stxB genes in STEC strains are located on the genomes of resident prophages of the lambda family immediately downstream of the phage late promoters (p(R')). The phage-encoded Q proteins modify RNA polymerase initiating...
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