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Bacteriophages Carrying Shiga Toxin Genes: Genomic Variations, Detection and Potential Treatment of Pathogenic Bacteria

1 Aug 2011

Abstract excerpt

Although most Escherichia coli strains occur in the mammalian intestine as commensals, some of them, including enterohemorrhagic E. coli (EHEC), are capable of causing disease in humans. The most notorious virulence factors of EHEC are Shiga toxins, encoded by genes located on genomes of lambdoid prophages. Production and release of these toxins is strongly stimulated after the induction of these prophages. Many...

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PMID: 21861621
DOI: 10.2217/fmb.11.70

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