Article
The orthologs of HLA-DQ and -DP genes display abundant levels of variability in macaque species.
Immunogenetics - 1 Feb 2017
Otting Nel, van der Wiel Marit K H, de Groot Nanine, de Vos-Rouweler Annemiek J M, de Groot Natasja G, Doxiadis Gaby G M, Wiseman Roger W, O'Connor David H, Bontrop Ronald E
Abstract excerpt
The human major histocompatibility complex (MHC) region encodes three types of class II molecules designated HLA-DR, -DQ, and -DP. Both the HLA-DQ and -DP gene region comprise a duplicated tandem of A and B genes, whereas in macaques, only one set of genes is present per region. A substantial sequencing project on the DQ and DP genes in various macaque populations resulted in the detection of previously 304...
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