Article
Polymorphism of the IGHA gene in sheep.
Immunogenetics - 1 Jul 2005
Zhou Huitong, Hickford Jon G H, Fang Qian
Abstract excerpt
Genetic variation in immunoglobulin A, the most abundant immunoglobulin in mammalian cells, has not been reported in ruminants. In this study, variation in the immunoglobulin heavy alpha chain constant gene (IGHA) of sheep was investigated by amplification of a fragment that included the hinge coding sequence, followed by single-strand conformational polymorphism (SSCP) analysis and DNA sequencing. Three novel...
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