Article
Features of microsatellite instability in colorectal cancer: comparison between colon and rectum.
Oncology - 1 Jan 2001
Ikeda Y, Oda S, Abe T, Ohno S, Maehara Y, Sugimachi K
Abstract excerpt
In one third of colorectal cancer patients, tumours occur in the rectum. Unique aetiologies may underlie the increased carcinogenesis in this region of the colorectum. Microsatellite instability (MSI) was analysed in specimens obtained from 121 colorectal carcinoma patients, using five dinucleotide markers and a new fluorescent system. The incidence of microsatellite alterations in the proximal colon, the distal...
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