Drosophila RNase H1 is essential for development but not for proliferation.

doi:10.1007/s004380100483

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Drosophila RNase H1 is essential for development but not for proliferation.

Molecular genetics and genomics : MGG - 1 Jul 2001

Filippov V, Filippov M, Gill S S

Abstract excerpt

Ribonucleases H (RNases H) recognize and specifically degrade RNA that is bound to complementary DNA and are thought to be involved in DNA replication and transcriptional regulation. Though it was previously shown that bacterial RNases H participate in DNA synthesis, none of the known mutations in RNase H genes in either prokaryotes or lower eukaryotes is lethal. Here, we report the characterization of the first...

Topics

Animals
Cell Differentiation
Cell Division
DNA Replication
Drosophila melanogaster
Gene Expression Regulation, Developmental
Genes, Insect
Mutation
Ribonuclease H

Source

Open in PubMed

Identifiers

PMID: 11523794
DOI: 10.1007/s004380100483

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics