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Article

Drosophila as a Model Organism to Understand the Effects during Development of TFIIH-Related Human Diseases.

International journal of molecular sciences - 17 Jan 2020

Zurita Mario, Murillo-Maldonado Juan Manuel

Abstract excerpt

Human mutations in the transcription and nucleotide excision repair (NER) factor TFIIH are linked with three human syndromes: xeroderma pigmentosum (XP), trichothiodystrophy (TTD) and Cockayne syndrome (CS). In particular, different mutations in the XPB, XPD and p8 subunits of TFIIH may cause one or a combination of these syndromes, and some of these mutations are also related to cancer. The participation of...

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Identifiers

PMID: 31963603
DOI: 10.3390/ijms21020630
PMCID: PMC7013941

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Drosophila as a Model Organism to Understand the Effects during Development of TFIIH-Related Human Diseases.PMID 31963603Read ↗

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