Article
Histone H1 is dispensable for methylation-associated gene silencing in Ascobolus immersus and essential for long life span.
Molecular and cellular biology - 1 Jan 2000
Barra J L, Rhounim L, Rossignol J L, Faugeron G
Abstract excerpt
A gene encoding a protein that shows sequence similarity with the histone H1 family only was cloned in Ascobolus immersus. The deduced peptide sequence presents the characteristic three-domain structure of metazoan linker histones, with a central globular region, an N-terminal tail, and a long positively charged C-terminal tail. By constructing an artificial duplication of this gene, named H1, it was possible to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
