Article
Polymorphisms in the insulin response element of APOC-III gene promoter influence the correlation between insulin and triglycerides or triglyceride-rich lipoproteins in humans.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Jul 2001
Dallongeville J, Meirhaeghe A, Cottel D, Fruchart J C, Amouyel P, Helbecque N
Abstract excerpt
OBJECTIVE: To assess whether the -455 and -482 mutations in APOC-III gene insulin response element affect the relationships between plasma insulin and triglyceride-rich lipoprotein levels. DESIGN: Population-based studies. SUBJECTS: The population sample was composed of 983 subjects (485 men and 498 women), aged between 35 and 65 y, randomly sampled from the electoral rolls in Northern France and stratified on...
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