Article
Serotonin transporter promoter polymorphism, peripheral indexes of serotonin function, and personality measures in families with alcoholism.
American journal of medical genetics - 8 Mar 2002
Stoltenberg Scott F, Twitchell Geoffrey R, Hanna Gregory L, Cook Edwin H, Fitzgerald Hiram E, Zucker Robert A, Little Karley Y
Abstract excerpt
A functional polymorphism in the regulatory region of the serotonin transporter gene (5-HTTLPR) is considered to be a plausible candidate gene for anxiety-related personality traits and for alcoholism. Empirical support for the association between 5-HTTLPR and psychological traits has been somewhat inconsistent; however, observations of the functional dominance of the low-activity s-allele over the l-allele have...
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