Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample.

American journal of medical genetics - 3 Apr 2000

Greenberg B D, Li Q, Lucas F R, Hu S, Sirota L A, Benjamin J, Lesch K P, Hamer D, Murphy D L

Abstract excerpt

The serotonin transporter (5-HTT) regulates serotonergic neurotransmission and is thought to influence emotion. A 5-HTT-linked polymorphic region (5-HTTLPR) has two common variants, short (s) and long (l). We previously found population and within-family associations between the lower-expressing s allele and neuroticism, a trait related to anxiety, hostility, and depression, on a standard measure (the NEO...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anxiety
Share to Demography

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Neurotic Disorders

Share to Nuclear Family

Share to Personality

Share to Personality Assessment

Share to Serotonin

Share to Serotonin Plasma Membrane Transport Proteins

Source

Identifiers

PMID: 10893498
DOI: 10.1002/(sici)1096-8628(20000403)96:2<202::aid-ajmg16>3.0.co;2-j

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample.PMID 10893498Read ↗

Meta-analysis of the association between a serotonin transporter promoter polymorphism (5-HTTLPR) and anxiety-related personality traits.Semantic proximity Read ↗

Gender differences in association between serotonin transporter gene polymorphism and personality traits.Semantic proximity Read ↗

Anxiety- and novelty seeking-related personality traits and serotonin transporter gene polymorphisms.Semantic proximity Read ↗

Association of a functional polymorphism in the serotonin transporter gene with personality traits in females in a Polish population.Semantic proximity Read ↗

Association between allelic variation of serotonin transporter function and neuroticism in anxious cluster C personality disorders.Semantic proximity Read ↗

Gender-specific association between serotonin transporter polymorphisms (5-HTTLPR and rs25531) and neuroticism, anxiety and depression in well-defined healthy Han Chinese.Semantic proximity Read ↗

Variants of the serotonin transporter gene and NEO-PI-R Neuroticism: No association in the BLSA and SardiNIA samples.Semantic proximity Read ↗

Role of the Serotonin Transporter Promoter Polymorphism in Anxiety-Related TraitsSemantic proximity Read ↗

Association between a serotonin transporter promoter polymorphism (5HTTLPR) and personality disorder traits in a community sample.Semantic proximity Read ↗

Allelic variation in 5-HT1A receptor expression is associated with anxiety- and depression-related personality traits.Semantic proximity Read ↗

No association of a functional polymorphism in the serotonin transporter gene promoter and anxiety-related personality traits.Semantic proximity Read ↗

Personality and the serotonin transporter gene: Associations in a longitudinal population-based study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.