Article
TNF-alpha and hyperandrogenism: a clinical, biochemical, and molecular genetic study.
The Journal of clinical endocrinology and metabolism - 1 Aug 2001
Escobar-Morreale H F, Calvo R M, Sancho J, San Millán J L
Abstract excerpt
To evaluate the role of TNF-alpha in the pathogenesis of hyperandrogenism, we have evaluated the serum TNF-alpha levels, as well as several polymorphisms in the promoter region of the TNF-alpha gene, in a group of 60 hyperandrogenic patients and 27 healthy controls matched for body mass index. Hyperandrogenic patients presented with mildly increased serum TNF-alpha levels as compared with controls (mean[median]...
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