Article
Excessive fat accumulation is associated with the TNF alpha-308 G/A promoter polymorphism in women but not in men.
Diabetologia - 1 Jan 2000
Hoffstedt J, Eriksson P, Hellström L, Rössner S, Rydén M, Arner P
Abstract excerpt
AIMS/HYPOTHESIS: Tumour necrosis factor alpha (TNF alpha) is a candidate gene for the development of obesity, which in turn is a major risk factor for diabetes mellitus. The aim of our study was to investigate whether a previously known NcoI-sensitive polymorphism (-308 G/A) in the promoter regio...
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