Article
Cartilage and bone changes during development of post-traumatic osteoarthritis in selected LGXSM recombinant inbred mice.
Osteoarthritis and cartilage - 1 Jun 2012
Hashimoto S, Rai M F, Janiszak K L, Cheverud J M, Sandell L J
Abstract excerpt
INTRODUCTION: Little evidence is available on the natural course of osteoarthritis (OA) development and the genes that protect and predispose individuals to it. This study was designed to compare strain-dependent development of OA and its association with tissue regeneration in mice. Two recombinant inbred lines LGXSM-6 and LGXSM-33 generated from LG/J and SM/J intercross were used. Previous studies indicated...
Topics
- Animals
- Arthritis, Experimental
- Bone and Bones
- Cartilage, Articular
- Ear, External
- Genetic Predisposition to Disease
- Male
- Medial Collateral Ligament, Knee
- Mice
- Mice, Inbred Strains
- Osteoarthritis
- Regeneration
- Species Specificity