Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship.

Osteoarthritis and cartilage - 1 Aug 2020

Rai M F, Cheverud J M, Schmidt E J, Sandell L J

Abstract excerpt

OBJECTIVE: The etiology of osteoarthritis (OA) is unknown, however, there appears to be a significant contribution from genetics. We have identified recombinant inbred strains of mice derived from LG/J (large) and SM/J (small) strains that vary significantly in their ability to repair articular cartilage and susceptibility to post-traumatic OA due to their genetic composition. Here, we report cartilage repair...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cartilage, Articular
Share to Disease Models, Animal
Share to Ear, External

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred Strains

Share to Osteoarthritis, Knee

Share to Regeneration

Share to Wound Healing

Source

Open in PubMed Open full text

Identifiers

PMID: 32437968
DOI: 10.1016/j.joca.2020.04.013
PMCID: PMC7387169

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic correlations between cartilage regeneration and degeneration reveal an inverse relationship.PMID 32437968Read ↗

Cartilage and bone changes during development of post-traumatic osteoarthritis in selected LGXSM recombinant inbred mice.Semantic proximity Read ↗

Heritability of articular cartilage regeneration and its association with ear wound healing in mice.Semantic proximity Read ↗

Molecular insight into the association between cartilage regeneration and ear wound healing in genetic mouse models: targeting new genes in regeneration.Semantic proximity Read ↗

Comparative Transcriptomics Identifies Novel Genes and Pathways Involved in Post-Traumatic Osteoarthritis Development and ProgressionSemantic proximity Read ↗

RNA-seq analysis of chondrocyte transcriptome reveals genetic heterogeneity in LG/J and SM/J murine strains.Semantic proximity Read ↗

Intramembranous bone regeneration in diversity outbred mice is heritable.Semantic proximity Read ↗

Genetic loci that regulate ectopic calcification in response to knee trauma in LG/J by SM/J advanced intercross mice.Semantic proximity Read ↗

Comparison of inbred mouse strains shows diverse phenotypic outcomes of intervertebral disc aging.Semantic proximity Read ↗

Genetic analysis of a mammalian wound-healing trait.Semantic proximity Read ↗

New quantitative trait loci that regulate wound healing in an intercross progeny from DBA/1J and 129 x 1/SvJ inbred strains of mice.Semantic proximity Read ↗

The STR/ort mouse model of spontaneous osteoarthritis - an update.Semantic proximity Read ↗

Differential patterns of pathology in and interaction between joint tissues in long-term osteoarthritis with different initiating causes: phenotype matters.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.