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Article

Structure of an active soluble mutant of the membrane-associated (S)-mandelate dehydrogenase.

Biochemistry - 21 Aug 2001

Sukumar N, Xu Y, Gatti D L, Mitra B, Mathews F S

Abstract excerpt

The structure of an active mutant of (S)-mandelate dehydrogenase (MDH-GOX2) from Pseudomonas putida has been determined at 2.15 A resolution. The membrane-associated flavoenzyme (S)-mandelate dehydrogenase (MDH) catalyzes the oxidation of (S)-mandelate to give a flavin hydroquinone intermediate which is subsequently reoxidized by an organic oxidant residing in the membrane. The enzyme was rendered soluble by...

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Identifiers

PMID: 11502180
DOI: 10.1021/bi010938k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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