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Article

Structural and functional studies on Troponin I and Troponin C interactions.

Journal of cellular biochemistry - 1 Jan 2000

Ngai S M, Pearlstone J R, Farah C S, Reinach F C, Smillie L B, Hodges R S

Abstract excerpt

Troponin I (TnI) peptides (TnI inhibitory peptide residues 104-115, Ip; TnI regulatory peptide resides 1-30, TnI1-30), recombinant Troponin C (TnC) and Troponin I mutants were used to study the structural and functional relationship between TnI and TnC. Our results reveal that an intact central D/E helix in TnC is required to maintain the ability of TnC to release the TnI inhibition of the acto-S1-TM ATPase...

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Identifiers

PMID: 11500952
DOI: 10.1002/jcb.1204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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