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Article

Ca2+-dependent interaction of the inhibitory region of troponin I with acidic residues in the N-terminal domain of troponin C.

Biochimica et biophysica acta - 19 Mar 1999

Kobayashi T, Zhao X, Wade R, Collins J H

Abstract excerpt

Ca2+ regulation of vertebrate striated muscle contraction is initiated by conformational changes in the N-terminal, regulatory domain of the Ca2+-binding protein troponin C (TnC), altering the interaction of TnC with the other subunits of troponin complex, TnI and TnT. We have investigated the role of acidic amino acid residues in the N-terminal, regulatory domain of TnC in binding to the inhibitory region...

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Identifiers

PMID: 10082949
DOI: 10.1016/s0167-4838(99)00002-3

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Ca2+-dependent interaction of the inhibitory region of troponin I with acidic residues in the N-terminal domain of troponin C.PMID 10082949Read ↗

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