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Article

Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T.

The Journal of biological chemistry - 12 Mar 1999

Hinkle A, Goranson A, Butters C A, Tobacman L S

Abstract excerpt

Striated muscle contraction is regulated by Ca2+ binding to troponin, which has a globular domain and an elongated tail attributable to the NH2-terminal portion of the bovine cardiac troponin T (TnT) subunit. Truncation of the bovine cardiac troponin tail was investigated using recombinant TnT fragments and subunits TnI and TnC. Progressive truncation of the troponin tail caused progressively weaker binding of...

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Source

Identifiers

PMID: 10066775
DOI: 10.1074/jbc.274.11.7157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Roles for the troponin tail domain in thin filament assembly and regulation. A deletional study of cardiac troponin T.PMID 10066775Read ↗

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