Expression of the CT/CGRP gene and its regulation by dibutyryl cyclic adenosine monophosphate in human osteoblastic cells.

doi:10.1359/jbmr.1997.12.11.1805

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Article

Expression of the CT/CGRP gene and its regulation by dibutyryl cyclic adenosine monophosphate in human osteoblastic cells.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 1997

Drissi H, Hott M, Marie P J, Lasmoles F

Abstract excerpt

There is general agreement that calcitonin (CT) inhibits bone resorption by its effects on osteoclast function. CT was also found to have direct effects on osteoblast-like cells. In this study, we investigated the expression of CT and calcitonin gene-related peptide (CGRP), the two peptides encod...

Topics

Alkaline Phosphatase
Bone Neoplasms
Bucladesine
Calcitonin
Calcitonin Gene-Related Peptide
Cell Differentiation
Cell Division
Cyclic AMP-Dependent Protein Kinases
Enzyme Activation
Gene Expression Regulation
Humans
Osteoblasts
Osteocalcin
Osteosarcoma
Phenotype
RNA, Messenger
Transcription, Genetic
Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 9383685
DOI: 10.1359/jbmr.1997.12.11.1805

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9383685-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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