Article
Induction of a senescence-like phenotype in bovine aortic endothelial cells by ionizing radiation.
Radiation research - 1 Sept 2001
Oh C W, Bump E A, Kim J S, Janigro D, Mayberg M R
Abstract excerpt
Treatment of confluent monolayers of bovine aortic endothelial cells (BAEC) with gamma rays resulted in the delayed appearance of cells with an enlarged surface area that were morphologically similar to senescent cells. The majority of these cells stained positively for senescence-associated beta-galactosidase (SA-beta-gal), indicating that these cells are biochemically similar to senescent cells. The incidence...
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