Article
A D(V)-like phenotype is obliterated by A226P in the partial D DBS.
Transfusion - 1 Aug 2001
Wagner F F, Ernst M, Sonneborn H H, Flegel W A
Abstract excerpt
BACKGROUND: In D category V types, the RHD exon 5 or parts thereof are replaced by the corresponding RHCE DNA segments. In D category V types I and II, the amino acid at position 226 is alanine, which is typical of the prevalent RHD allele and is observed in all RHCE alleles encoding the antigen e. A proline at position 226 in RHCE encodes the antigen E. STUDY DESIGN AND METHODS: A blood sample of ccDEe phenotype...
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