Article
The DAU cluster: a comparative analysis of 18 RHD alleles, some forming partial D antigens.
Transfusion - 1 Oct 2016
Srivastava Kshitij, Polin Helene, Sheldon Sherry Lynne, Wagner Franz Friedrich, Grabmer Christoph, Gabriel Christian, Denomme Gregory Andrew, Flegel Willy Albert
Abstract excerpt
BACKGROUND: The Rh system is the most complex and polymorphic blood group system in humans with more than 460 alleles known for the RHD gene. The DAU cluster of RHD alleles is characterized by the single-nucleotide change producing the p.Thr379Met amino acid substitution. It is called the DAU-0 allele and has been postulated to be the primordial allele, from which all other alleles of the DAU cluster have...
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