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Article

D variants at the RhD vestibule in the weak D type 4 and Eurasian D clusters.

Transfusion - 1 Jun 2009

Flegel Willy A, von Zabern Inge, Doescher Andrea, Wagner Franz F, Strathmann Klaus P, Geisen Christof, Palfi Miodrag, Písacka Martin, Poole Joyce, Polin Helene, Gabriel Christian, Avent Neil D

Abstract excerpt

BACKGROUND: One branch of the RHD phylogenetic tree is represented by the weak D type 4 cluster of alleles with F223V as the primordial amino acid substitution. F223V as well as a large number of further substitutions causing D variants are located at the extracellular RhD protein vestibule, which represents the entrance to the transmembraneous channel of the RhD protein. STUDY DESIGN AND METHODS: RHD and RHCE...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19309476
DOI: 10.1111/j.1537-2995.2009.02102.x
PMCID: PMC10710224

Genes

RHD
RHCE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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