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Article

Role of endogenous nitric oxide in liver-specific functions and survival of cultured rat hepatocytes.

Xenobiotica; the fate of foreign compounds in biological systems - 1 May 2001

Donato M T, Ponsoda X, O'Connor E, Castell J V, Gómez-Lechón M J

Abstract excerpt

1. The role of endogenous nitric oxide in rat hepatocyte functionality and survival in cell culture was examined. Towards this aim, cytochrome P450 activities (CYP1A1/2, 2B1, 2A1, 2C11, 2D1, 2E1 and 3A1), liver-specific metabolic functions and cell survival were comparatively evaluated in hepatocytes isolated from the male Sprague-Dawley rat and/or cultured in control conditions or in the presence of...

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PMID: 11491387
DOI: 10.1080/00498250110052111

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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