Article
Real-Time Imaging of Vascular Endothelial-Cadherin During Leukocyte Transmigration Across Endothelium
1 Aug 2001
Abstract excerpt
Vascular endothelial-cadherin (VE-cadherin) is a component of the adherens junctions of endothelial cells whose role in endothelial transmigration of leukocytes has been controversial. Using a VE-cadherin/green fluorescent protein fusion construct (VEcadGFP) that mimics the native molecule, we visualized alterations in endothelial junctional structure in real time during transmigration of human neutrophils and...
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